Type 1 Diabetes TrialNet

(888) 884-8638

If your child is a family member of someone with type-1 diabetes, there’s a greater risk he or she could develop this disease. Children’s Hospital wants you to know about a free screening program that could identify this risk and help you take positive steps toward improving your child’s health.

Type 1 Diabetes TrialNet is a network of major research centers. Its goal is to find the causes of type-1 diabetes, and to work toward prevention and early treatment of this disease.

Vanderbilt University Medical Center is TrialNet research network Major Affiliate and Clinical Center. By working together with other research centers around the world, there is hope for improving the lives of those with type-1 diabetes much more quickly.

TrialNet receives funding from the National Institutes of Health, the Juvenile Diabetes Research Foundation, and the American Diabetes Association.

How TrialNet works

TrialNet’s worldwide network of healthcare providers offers screening for family members of persons who have been diagnosed with type-1 diabetes. These screenings take place at no cost throughout the U.S. at locations convenient to you.

TrialNet’s screenings create no medical records of individuals screened. There are also no medical bills involved.

TrialNet hopes to achieve three goals through these screenings.

  1. Find persons at higher risk for developing type-1 diabetes.
  2. Find persons who may be a good fit for TrialNet studies on preventing or delaying the onset of this disease.
  3. Learn more about what happens in the body of a person in the months and years prior to the disease’s development.

TrialNet’s screening processes can detect the presence of autoantibodies years before type-1 diabetes would be diagnosed. With this information, you and your healthcare provider could be better prepared for the disease’s onset. Identifying your child as likely to develop type-1 diabetes may also make your family eligible for further studies as TrialNet works toward preventive measures and cures.

How to know if you’re right for the TrialNet study

TrialNet is seeking children and adults for this study. Eligibility is open to persons who have a close blood relative who has been diagnosed with type-1 diabetes.

TrialNet may be interested in screening you or your child if

  • Are between the ages of 2 years 6 months and 45 years and have a sibling, child, or parent with type-1 diabetes.
  • Are between the ages of 2 years 6 months and 20 years, and have a niece, nephew, aunt, uncle, grandparent, cousin or half-sibling with type-1 diabetes.

Individuals may not be eligible for this study if they take

  • Medicine to lower your blood glucose.
  • Medicine that affects your immune system.
  • Steroidal medications, possibly including asthma inhalers.

How to register for TrialNet

Call 615-936-TNET or 888-VU4-TNET, or email diabetesresearch@vumc.org to arrange phone consent and assent for participation.

What happens at a TrialNet screening

We require about a tablespoon of blood from eligible children and adults. These blood draws can be done at the Eskind Diabetes Clinic, or at other TrialNet sites, or by TrialNet staff at diabetes camps and walks, or other similar events.

If you prefer, TrialNet can also send you a screening kit you can take to your family doctor or local lab. The kit includes instructions on returning it to TrialNet. Once returned, TrialNet screens blood samples for autoantibodies. Results become available within four to six weeks.

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